@b1inchrist First, I just want to say I totally understand how hard and stressful this decision is and I’m sorry you are having to go through this. Husband and I are both 36, unexplained infertility, and RE recommended to go straight to IVF. We decided to try the 3 rounds of IUI that insurance covers anyway, just for the peace of mind that we tried the lower tier intervention before jumping to IVF. We’re on our 3rd and final IUI now (fingers crossed it works!) and I don’t regret trying it. The meds are less intensive than IVF but still come with their own mood swings/side effects. Benefit to IVF is that you can do genetic screenings of your embryo before transfer to reduce risks of genetic abnormalities/miscarriage, and that you may get more embryos for future children with younger, healthier eggs. I’ve been told IVF can take 4 months (at minimum, if all goes well) to prep for before a transfer, to factor that into your decision. r/infertility is a great resource if you aren’t already part of that community too.